R Final Project - Group 11

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Introduction

• Source of the dataset: MiRNA expression in squamous cell carcinoma and adenocarcinoma of the esophagus and associations with survival.

  • Microarray data from cancerous and adjacent noncancerous tissues collected from 100 adenocarcinoma and 70 SCC patients enrolled at four clinical centers from the United States, Canada, and Japan

• Objective of the project: To reproduce the findings of the authors and elaborate on their visualizations.

Materials and methods | Patient data:

• GSE13937_series_matrix.txt
  

• National Center for Biotechnology Information website (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE13937)

Microarray information:

• A-GEOD-8835.adf.txt and A-GEOD-8835_comments.txt

• European Bioinformatics Institute website (https://www.ebi.ac.uk/arrayexpress/arrays/A-GEOD-8835/)

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Materials and methods | Flowchart of the development process

Results

summary(cars)

##      speed           dist       
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Methods: pipeline flowchart





Results


summary(cars)

##      speed           dist       
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##  Min.   : 4.0   Min.   :  2.00  
##  1st Qu.:12.0   1st Qu.: 26.00  
##  Median :15.0   Median : 36.00  
##  Mean   :15.4   Mean   : 42.98  
##  3rd Qu.:19.0   3rd Qu.: 56.00  
##  Max.   :25.0   Max.   :120.00

Results

Results

Results

Discussion

Discussion